Article
Delayed decline of gamma-globin expression in infant age associated with the presence of Ggamma-158 (C-->T) polymorphism.
International journal of laboratory hematology - 1 Jun 2008
Grosso M, Amendolara M, Rescigno G, Danise P, Todisco N, Izzo P, Amendola G
Abstract excerpt
Persistent production of fetal hemoglobin (HbF) in adult has ameliorative effects on hemoglobinopathies and great efforts are currently made to achieve an exhaustive understanding of the molecular mechanisms of the switching in globin gene expression. One of the factors reported to be associated with the expression of fetal globin genes is the Xmn I Ggamma-158 polymorphism, although it is still unclear if it is...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
