Variability in the fetal hemoglobin level of the normal adult.

doi:10.1002/(SICI)1096-8652(199610)53:2<59::AID-AJH1>3.0.CO;2-2

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Article

Variability in the fetal hemoglobin level of the normal adult.

American journal of hematology - 1 Oct 1996

Leonova JYe, Kazanetz E G, Smetanina N S, Adekile A D, Efremov G D, Huisman T H

Abstract excerpt

We analyzed blood samples from more than 200 normal adults, and quantified their Hb F by cation-exchange high-performance liquid chromatography. In several subjects with slightly elevated Hb F (0.4-4.3%), we determined the Ggamma levels in the Hb F and DNA sequence variations in the locus control region II and in the Ggamma and Agamma promoters. About 25% of the approximately 200 normal teenaged high school...

Topics

Adolescent
Adult
Child
Chromatography, High Pressure Liquid
Female
Fetal Hemoglobin
Humans
Male
Multigene Family
Mutation
Promoter Regions, Genetic
Reference Values

Source

Open in PubMed

Identifiers

PMID: 8892728
DOI: 10.1002/(SICI)1096-8652(199610)53:2<59::AID-AJH1>3.0.CO;2-2

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