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Article

Manganese superoxide dismutase gene coding region polymorphisms lack clinical incidence in general population.

DNA and cell biology - 1 Jun 2008

Martin Robert C G, Barker David F, Doll Mark A, Pine Sharon R, Mechanic Leah, Bowman Elise D, Harris Curtis C, Hein David W

Abstract excerpt

Two functional polymorphisms within the manganese superoxide dismutase (MnSOD) gene have been reported to lead to increased oxidative stress damage. The MnSOD 58T > C single nucleotide polymorphism (SNP) within exon 3 changes isoleucine to threonine, leading to decreased thermal stability and reduced enzymatic activity in vivo and in vitro. The MnSOD 60C > T polymorphism within exon 3 changes leucine to...

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Identifiers

PMID: 18466086
DOI: 10.1089/dna.2007.0725
PMCID: PMC2576292

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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