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C47T polymorphism in manganese superoxide dismutase (MnSOD), antioxidant intake and survival.

Mechanisms of ageing and development - 1 Apr 2006

Genkinger Jeanine M, Platz Elizabeth A, Hoffman Sandy C, Strickland Paul, Huang Han-Yao, Comstock George W, Helzlsouer Kathy J

Abstract excerpt

INTRODUCTION AND OBJECTIVE: Manganese superoxide dismutase (MnSOD), an enzyme that catalyzes superoxide radical quenching, is hypothesized to protect against premature aging. A C47T transition in the MnSOD gene may affect the enzyme's distribution to the mitochondrion, a site of high oxidative st...

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PMID: 16458347
DOI: 10.1016/j.mad.2005.12.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16458347-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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