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Article

Method for determination of (-102C>T) single nucleotide polymorphism in the human manganese superoxide dismutase promoter.

BMC genetics - 14 Dec 2004

Martin Robert C G, Hughes Kalista, Doll Mark A, Lan Qing, Martini Benjamin D, Lissowska Jolanta, Rothman Nathaniel, Hein David W

Abstract excerpt

BACKGROUND: Manganese superoxide dismutase (MnSOD) plays a critical role in the detoxification of mitochondrial reactive oxygen species constituting a major cellular defense mechanism against agents that induce oxidative stress. The MnSOD promoter contains an activator protein-2 (AP-2) binding site that modifies transcription of MnSOD. Mutations have been identified in the proximal region of the promoter in human...

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Identifiers

PMID: 15598343
DOI: 10.1186/1471-2156-5-33
PMCID: PMC544190

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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