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Article

PAI-1 donor polymorphism influences long-term kidney graft survival.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Oct 2008

Rérolle Jean-Philippe, Munteanu Elisa, Drouet Mireille, Szelag Jean-Christophe, Champtiaux Béatrice, Yagoubi Fatima, Preux Pierre-Marie, Aldigier Jean-Claude, Le Meur Yann

Abstract excerpt

BACKGROUND: The type 1 plasminogen activator inhibitor (PAI-1) is involved in the development of fibrosis, and its intrarenal expression is increased in interstitial fibrosis and tubular atrophy (IFTA). Moreover, a 4G/5G polymorphism of the PAI-1 gene has been described associating 4G haplotype with higher PAI-1 plasma activity. We investigated the relationship between the donor and recipient PAI-1 polymorphism...

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Identifiers

PMID: 18463321
DOI: 10.1093/ndt/gfn241

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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