Article
The interleukin-6 -174promoter polymorphism is associated with long-term kidney allograft survival.
Kidney international - 1 Nov 2002
Müller-Steinhardt Michael, Härtel Christoph, Müller Brigitte, Kirchner Holger, Fricke Lutz
Abstract excerpt
BACKGROUND: Th1-dependent effector mechanisms may be responsible for allograft rejection. Recently, interleukin-6 (IL-6) has been shown to antagonize CD4+ T cells to effector Th2 cells and, in the process, differentiate them into Th1 cells. METHODS: To assess the role of IL-6 in long-term allogra...
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