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A functional <i>TGFB1</i> polymorphism in the donor associates with long-term graft survival after kidney transplantation

2021-07-07

Abstract excerpt

<h4>Introduction</h4> Improvement of long-term outcomes in kidney transplantation remains one of the most pressing challenges, yet drug development is stagnating. Human genetics offers an opportunity for much-needed target validation in transplantation. Conflicting data exist about the effect of transforming growth factor-beta 1 (TGF-β1) on kidney transplant survival since TGF-β1 has pro-fibrotic and protective ef...

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Literature Corpus work
266fdde1-408f-55ee-852d-acf5dcd9329d
DOI
10.1101/2021.07.05.21260045
Open publication

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A functional <i>TGFB1</i> polymorphism in the donor associates with long-term graft survival after kidney transplantationDOI 10.1101/2021.07.05.21260045
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