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Article

Crippling HIV one mutation at a time.

The Journal of experimental medicine - 12 May 2008

Allen Todd M, Altfeld Marcus

Abstract excerpt

Accumulating data suggest that not all human immunodeficiency virus (HIV)-1-specific immune responses are equally effective at controlling HIV-1 replication. A new study now demonstrates that multiple immune-driven sequence polymorphisms in the highly conserved HIV-1 Gag region of transmitted viruses are associated with reduced viral replication in newly infected humans. These data suggest that targeting these...

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Identifiers

PMID: 18458116
DOI: 10.1084/jem.20080569
PMCID: PMC2373833

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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