Article
The Mediator subunit MDT-15 confers metabolic adaptation to ingested material.
PLoS genetics - 29 Feb 2008
Taubert Stefan, Hansen Malene, Van Gilst Marc R, Cooper Samantha B, Yamamoto Keith R
Abstract excerpt
In eukaryotes, RNA polymerase II (Pol(II)) dependent gene expression requires accessory factors termed transcriptional coregulators. One coregulator that universally contributes to Pol(II)-dependent transcription is the Mediator, a multisubunit complex that is targeted by many transcriptional regulatory factors. For example, the Caenorhabditis elegans Mediator subunit MDT-15 confers the regulatory actions of the...
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