Article
Methylmercury Induces Metabolic Alterations in Caenorhabditis elegans: Role for C/EBP Transcription Factor.
Toxicological sciences : an official journal of the Society of Toxicology - 1 Mar 2020
Caito Samuel W, Newell-Caito Jennifer, Martell Megan, Crawford Nicole, Aschner Michael
Abstract excerpt
Methylmercury (MeHg) is a well-known neurotoxicant; however, its role in metabolic diseases has been gaining wider attention. We have previously shown that MeHg causes metabolic alterations in Caenorhabditis elegans, leading to decreased nicotinamide adenine dinucleotide cofactor, mitochondrial dysfunction, and oxidative stress. We were, therefore, interested in whether MeHg also affects nutrient metabolism,...
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