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Article

Drosophila histone deacetylase-3 controls imaginal disc size through suppression of apoptosis.

PLoS genetics - 29 Feb 2008

Zhu Changqi C, Bornemann Douglas J, Zhitomirsky David, Miller Ellen L, O'Connor Michael B, Simon Jeffrey A

Abstract excerpt

Histone deacetylases (HDACs) execute biological regulation through post-translational modification of chromatin and other cellular substrates. In humans, there are eleven HDACs, organized into three distinct subfamilies. This large number of HDACs raises questions about functional overlap and division of labor among paralogs. In vivo roles are simpler to address in Drosophila, where there are only five HDAC...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18454196
DOI: 10.1371/journal.pgen.1000009
PMCID: PMC2265479

Genes

HDAC3
HDAC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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