Article
Physical and functional association of SU(VAR)3-9 and HDAC1 in Drosophila.
EMBO reports - 1 Oct 2001
Czermin B, Schotta G, Hülsmann B B, Brehm A, Becker P B, Reuter G, Imhof A
Abstract excerpt
Modification of histones can have a dramatic impact on chromatin structure and function. Acetylation of lysines within the N-terminal tail of the histone octamer marks transcriptionally active regions of the genome whereas deacetylation seems to play a role in transcriptional silencing. Recently, the methylation of the histone tails has also been shown to be important for transcriptional regulation and chromosome...
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