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Article

The Genetic Architecture of Quantitative Traits Cannot Be Inferred from Variance Component Analysis.

PLoS genetics - 1 Nov 2016

Huang Wen, Mackay Trudy F C

Abstract excerpt

Classical quantitative genetic analyses estimate additive and non-additive genetic and environmental components of variance from phenotypes of related individuals without knowing the identities of quantitative trait loci (QTLs). Many studies have found a large proportion of quantitative trait variation can be attributed to the additive genetic variance (VA), providing the basis for claims that non-additive gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27812106
DOI: 10.1371/journal.pgen.1006421
PMCID: PMC5094750

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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