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Article

Uniparental disomy may be associated with microsatellite instability in acute myeloid leukemia (AML) with a normal karyotype.

Leukemia & lymphoma - 1 Jun 2008

Serrano Elena, Carnicer Maria J, Orantes Vanesa, Estivill Camino, Lasa Adriana, Brunet Salut, Aventín Anna M, Sierra Jorge, Nomdedéu Josep F

Abstract excerpt

The discovery of underlying genetic lesions helps to better understand the mechanisms of leukemogenesis and identify prognostic subgroups. Recent insights have allowed normal karyotype acute myeloid leukemia (AML) to be split into many molecular entities according to the genetic status of FLT3, NPM, CEBPA and MLL. Genome-wide single nucleotide polymorphism analysis was performed on 22 well-characterised AML...

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Source

Identifiers

PMID: 18452069
DOI: 10.1080/10428190802035941

Genes

FLT3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Uniparental disomy may be associated with microsatellite instability in acute myeloid leukemia (AML) with a normal karyotype.PMID 18452069Read ↗

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