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Article

SNPs array karyotyping reveals a novel recurrent 20p13 amplification in primary myelofibrosis.

PloS one - 1 Jan 2011

Visani Giuseppe, Sapienza Maria Rosaria, Isidori Alessandro, Tripodo Claudio, Laginestra Maria Antonella, Righi Simona, Sagramoso Sacchetti Carlo A, Gazzola Anna, Mannu Claudia, Rossi Maura, De Nictolis Michele, Valentini Massimo, Donati Meris, Emiliani Roberto, Alesiani Francesco, Paolini Stefania, Finelli Carlo, Pileri Stefano A, Piccaluga Pier Paolo

Abstract excerpt

The molecular pathogenesis of primary mielofibrosis (PMF) is still largely unknown. Recently, single-nucleotide polymorphism arrays (SNP-A) allowed for genome-wide profiling of copy-number alterations and acquired uniparental disomy (aUPD) at high-resolution. In this study we analyzed 20 PMF patients using the Genome-Wide Human SNP Array 6.0 in order to identify novel recurrent genomic abnormalities. We observed...

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Share to Chromosomes, Human, Pair 20
Share to Gene Amplification

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Loss of Heterozygosity

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Share to Receptors, Cell Surface

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Source

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Identifiers

PMID: 22110671
DOI: 10.1371/journal.pone.0027560
PMCID: PMC3215741

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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