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Article

Novel regions of acquired uniparental disomy discovered in acute myeloid leukemia.

Genes, chromosomes & cancer - 1 Sept 2008

Gupta Manu, Raghavan Manoj, Gale Rosemary E, Chelala Claude, Allen Christopher, Molloy Gael, Chaplin Tracy, Linch David C, Cazier Jean-Baptiste, Young Bryan D

Abstract excerpt

The acquisition of uniparental disomy (aUPD) in acute myeloid leukemia (AML) results in homozygosity for known gene mutations. Uncovering novel regions of aUPD has the potential to identify previously unknown mutational targets. We therefore aimed to develop a map of the regions of aUPD in AML. H...

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Share to Chromosomes, Human, Pair 11
Share to Chromosomes, Human, Pair 13
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to FLT3 gene

Share to Leukemia, Myeloid, Acute

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Source

Identifiers

PMID: 18506749
DOI: 10.1002/gcc.20573

Genes

FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18506749-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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