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Article

Chromosomal lesions and uniparental disomy detected by SNP arrays in MDS, MDS/MPD, and MDS-derived AML.

Blood - 1 Feb 2008

Gondek Lukasz P, Tiu Ramon, O'Keefe Christine L, Sekeres Mikkael A, Theil Karl S, Maciejewski Jaroslaw P

Abstract excerpt

Using metaphase cytogenetics (MC), chromosomal abnormalities are found in only a proportion of patients with myelodysplastic syndrome (MDS). We hypothesized that with new precise methods more cryptic karyotypic lesions can be uncovered that may show important clinical implications. We have applied 250K single nucleotide polymorphisms (SNP) arrays (SNP-A) to study chromosomal lesions in samples from 174 patients...

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Share to Chromosomes, Human
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Karyotyping

Share to Leukemia, Myeloid, Acute

Share to Myelodysplastic Syndromes

Share to Myeloproliferative Disorders

Share to Oligonucleotide Array Sequence Analysis

Share to Uniparental Disomy

Source

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Identifiers

PMID: 17954704
DOI: 10.1182/blood-2007-05-092304
PMCID: PMC2214746

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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