Article
Correlation of EGFR mutations with chromosomal alterations and expression of EGFR, ErbB3 and VEGF in tumor samples of lung adenocarcinoma patients.
Lung cancer (Amsterdam, Netherlands) - 1 Nov 2008
Reinmuth Niels, Jauch Anna, Xu Elizabeth Chang, Muley Thomas, Granzow Martin, Hoffmann Hans, Dienemann Hendrik, Herpel Esther, Schnabel Philipp A, Herth Felix J F, Gottschling Sandra, Lahm Harald, Steins Martin, Thomas Michael, Meister Michael
Abstract excerpt
INTRODUCTION: Mutations in the tyrosine kinase domain of the epidermal growth factor receptor (EGFR) are frequently detected in lung adenocarcinomas with bronchioloalveolar (BAC) differentiation and have been associated with increased response to small molecule EGFR inhibitors in some clinical st...
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