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Article

Mapping EGFR1 mutations in patients with lung adenocarcinoma.

Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Dec 2010

Vlastos Fotis, Zinszner Julie, Hussenet Thomas, du Manoir Stanislas, Vordonis Leonidas, Nikolakopoulou Sofia, Hardavella Georgia, Lacomme Stéfanie, Vignaud Jean Michel, Martinet Nadine

Abstract excerpt

INTRODUCTION: Unselected lung cancer patients seem unable to gain in terms of survival from treatment with epidermal growth factor receptor (EGFR) inhibitors. Screening for specific molecular targets involves detection of EGFR1 mutations. The aim of our study was to develop a simple set of tests to detect mutations at the tyrosine kinase domain of the EGFR1 gene while avoiding expensive DNA sequencing to select...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21052000
DOI: 10.1097/PDM.0b013e3181d32605

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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