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Article

Clinicopathologic and prognostic significance of c-MYC copy number gain in lung adenocarcinomas

1 May 2014

Abstract excerpt

BACKGROUND: c-MYC copy number gain (c-MYC gain) has been associated with aggressive behaviour in several cancers. However, the role of c-MYC gain has not yet been determined in lung adenocarcinomas classified by genetic alterations in epidermal growth factor receptor (EGFR), KRAS, and anaplastic lymphoma kinase (ALK) genes. We investigated the clinicopathologic and prognostic significance of c-MYC gain for...

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PMID: 24809777
DOI: 10.1038/bjc.2014.218

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