Article
Chromosomal imbalances in lung adenocarcinomas with or without mutations in the epidermal growth factor receptor gene.
Respirology (Carlton, Vic.) - 1 May 2010
Fong Yao, Lin Yue-Shan, Liou Chiou-Ping, Li Chien-Fen, Tzeng Ching-Cherng
Abstract excerpt
BACKGROUND AND OBJECTIVE: Epidermal growth factor receptor (EGFR) mutations are common in lung adenocarcinomas of Asian patients, implying a good response to treatment with the EGFR tyrosine kinase inhibitors, gefitinib and erlotinib. However, the distinct chromosomal imbalances between lung adenocarcinomas with and those without EGFR mutations have not been fully elucidated. METHODS: Seventy-seven patients of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
