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Article

A 3'-untranslated region polymorphism in IGF1 predicts survival of non-small cell lung cancer in a Chinese population.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Feb 2010

Zhang Mingfeng, Hu Zhibin, Huang Jinlin, Shu Yongqian, Dai Juncheng, Jin Guangfu, Tang Rong, Dong Jing, Chen Yijiang, Xu Lin, Huang Xinen, Shen Hongbing

Abstract excerpt

PURPOSE: Disruption of the balance of insulin-like growth factor I (IGF-I) and IGF-binding protein 3 (IGFBP3) has been implicated in the etiology and progression of lung and other cancers. Single nucleotide polymorphisms (SNP) in IGF1 and IGFBP3 have been reported to be associated with the expression of the IGF-I/IGFBP3 axis. Therefore, we hypothesized that SNPs in these two genes were associated with lung cancer...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Non-Small-Cell Lung

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Source

Identifiers

PMID: 20145156
DOI: 10.1158/1078-0432.CCR-09-2719

Genes

IGF1
IGFBP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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