Impact of the IGFBP3 A-202C polymorphism on susceptibility and clinicopathologic features of breast cancer.

doi:10.1016/j.biopha.2015.02.018

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Article

Impact of the IGFBP3 A-202C polymorphism on susceptibility and clinicopathologic features of breast cancer.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Apr 2015

Ma Xiaobin, Kang Huafeng, Dai Zhijun, Ma Li, Jin Yaofeng, Wang Xijing

Abstract excerpt

BACKGROUND: Insulin-like growth factor binding protein 3 (IGFBP3) plays an important role in cellular proliferation, differentiation, apoptosis, and mammary carcinogenesis. Genetic variations in IGFBP3 have been identified to influence the circulating IGFBP3 level. The present study determined the impact of an important promoter polymorphism (A-202C, rs2854744) on susceptibility and progression of breast cancer...

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Identifiers

PMID: 25960224
DOI: 10.1016/j.biopha.2015.02.018

Genes

IGFBP3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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