Article
Association of cytotoxic T-lymphocyte antigen 4 gene polymorphisms with idiopathic thrombocytopenic purpura in a Chinese population.
Platelets - 1 Jan 2011
Li Huiyuan, Ge Jing, Zhao Haifeng, Du Weiting, Xu Jianhui, Sui Tao, Ma Li, Zhou Zeping, Qi Aiping, Yang Renchi
Abstract excerpt
Idiopathic thrombocytopenic purpura (ITP) is an acquired organ-specific autoimmune hemorrhagic disease with many immune dysfunctions. Cytotoxic T lymphocyte antigen 4 (CTLA-4) is a T-lymphocyte surface molecule that can down modulate and terminate immune responses. Recently, several studies have c...
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