Interferon-gamma gene polymorphism +874 (a/t) in Chinese children with Henoch-Schonlein purpura.

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Interferon-gamma gene polymorphism +874 (a/t) in Chinese children with Henoch-Schonlein purpura.

Iranian journal of allergy, asthma, and immunology - 1 Jun 2014

Xu Hui, Li Wei, Fu Haidong, Jiang Guizheng

Abstract excerpt

The aim of this study was to investigate the possible influence of Interferon-gamma (IFN-γ) gene polymorphism +874 (A/T) (rs2430561) in the susceptibility and renal complications of patients with Henoch-Schonlein purpura (HSP). We also studied the effects of IFN-γ allelic variation on serum levels of pro-and anti-inflammatory cytokines in HSP patients. The study population comprised 97 patients suffering from HSP...

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PMID: 24659122

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