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Article

The effect of CYP3A5 polymorphisms on the pharmacokinetics of tacrolimus in adolescent kidney transplant recipients.

Medical science monitor : international medical journal of experimental and clinical research - 1 May 2008

Tirelli Silvia, Ferraresso Mariano, Ghio Luciana, Meregalli Elisa, Martina Valentina, Belingheri Mirco, Mattiello Camilla, Torresani Emilio, Edefonti Alberto

Abstract excerpt

BACKGROUND: CYP3A5 gene polymorphism has been shown to influence tacrolimus (TAC) blood concentration and dose requirement in adult kidney transplant patients. The aim was to analyze retrospectively the modification induced by CYP3A5 gene polymorphism on TAC's pharmacokinetic parameters obtained...

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Source

Identifiers

PMID: 18443548

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18443548-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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