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Article

Effect of CYP3A5 genotype, steroids, and azoles on tacrolimus in a pediatric renal transplant population.

Pediatric nephrology (Berlin, Germany) - 1 Oct 2014

Lalan Shwetal, Abdel-Rahman Susan, Gaedigk Andrea, Leeder J Steven, Warady Bradley A, Dai Hongying, Blowey Douglas

Abstract excerpt

BACKGROUND: Numerous studies have described the impact of cytochrome P450 3A5 (CYP3A5) genotype on Tacrolimus (TAC) exposure. The purpose of this study was to conduct a comprehensive analysis of genetic and non-genetic factors affecting the TAC dose-exposure relationship over the first year post pediatric renal transplant. METHODS: Data were collected retrospectively for the first year post-transplant in...

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Identifiers

PMID: 24875272
DOI: 10.1007/s00467-014-2827-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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