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The pharmacogenetics of Tacrolimus in Algerian kidney recipients' patients.

Annales pharmaceutiques francaises - 1 Jun 2026

Fetati Habiba, Abderahmene Amani, Boudia Fatma, Zemour Lakhdar, Mekaouche Nadjet-Fatima-Zohra, Memou Asmaa, Djoudad Kada, Zerdoumi Faiza, Benslama Ali, Omezzine Asma, Toumi Houari

Abstract excerpt

BACKGROUND: The aim of this study was to evaluate the impact of CYP3A5*3(rs776746), CYP3A4*1B (rs2740574), CYP3A4*22 (rs35599367) and ABCB1 3435C>T (rs1045462) on Tacrolimus (Tac) pharmacokinetics in the Algerian kidney transplant population. MATERIALS AND METHODS: A retrospective and prospective cross-sectional study on only adult kidney recipient patients of Algerian origin who were treated with Tacrolimus...

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Share to Algeria
Share to ATP Binding Cassette Transporter, Subfamily B
Share to Cross-Sectional Studies
Share to Cytochrome P-450 CYP3A
Share to Immunosuppressive Agents
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Source

Identifiers

PMID: 41643888
DOI: 10.1016/j.pharma.2026.01.008

Genes

CYP3A4
CYP3A5
ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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