Article
Genetic predisposition, nongenetic risk factors, and coronary infarct.
Archives of internal medicine - 28 Apr 2008
Trichopoulou Antonia, Yiannakouris Nikos, Bamia Christina, Benetou Vassiliki, Trichopoulos Dimitrios, Ordovas Jose M
Abstract excerpt
BACKGROUND: Using a genetic predisposition score (GPS), additively integrating the associations of 11 polymorphisms with coronary heart disease (CHD), we examined the consequences of the joint presence of a high GPS and nongenetic CHD risk factors. METHODS: Within the European Prospective Investigation Into Cancer and Nutrition, 202 case patients with medically confirmed incident coronary infarct and 197 control...
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