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Article

Genetics, its role in preventing the pandemic of coronary artery disease.

Clinical cardiology - 1 Jun 2021

Roberts Robert, Fair Jacques

Abstract excerpt

Epidemiologists have claimed for decades that about 50% of predisposition for coronary artery disease (CAD) is genetic. Advances in technology made possible the discovery of hundreds of genetic risk variants predisposing to CAD. Multiple clinical trials have shown that cardiac events can be prevented by drugs to lower plasma low-density lipoprotein cholesterol (LDL-C). A major barrier to primary prevention is the...

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PMID: 34080689
DOI: 10.1002/clc.23627
PMCID: PMC8207986

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