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Article

In vitro evaluation of CBR-2092, a novel rifamycin-quinolone hybrid antibiotic: microbiology profiling studies with staphylococci and streptococci.

Antimicrobial agents and chemotherapy - 1 Jul 2008

Robertson Gregory T, Bonventre Eric J, Doyle Timothy B, Du Qun, Duncan Leonard, Morris Timothy W, Roche Eric D, Yan Dalai, Lynch A Simon

Abstract excerpt

We present data from antimicrobial assays performed in vitro that pertain to the potential clinical utility of a novel rifamycin-quinolone hybrid antibiotic, CBR-2092, for the treatment of infections mediated by gram-positive cocci. The MIC(90)s for CBR-2092 against 300 clinical isolates of staphylococci and streptococci ranged from 0.008 to 0.5 mug/ml. Against Staphylococcus aureus, CBR-2092 exhibited prolonged...

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Identifiers

PMID: 18443106
DOI: 10.1128/AAC.01651-07
PMCID: PMC2443883

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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