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Article

Antistaphylococcal activities of the new fluoroquinolone JNJ-Q2.

Antimicrobial agents and chemotherapy - 1 Dec 2011

Morrow Brian J, Abbanat Darren, Baum Ellen Z, Crespo-Carbone Steven M, Davies Todd A, He Wenping, Shang Wenchi, Queenan Anne Marie, Lynch A Simon

Abstract excerpt

The new broad-spectrum fluoroquinolone JNJ-Q2 displays in vitro activity against Gram-negative and Gram-positive organisms, including methicillin-resistant Staphylococcus aureus (MRSA) and ciprofloxacin-resistant MRSA isolates. Tested with isogenic methicillin-susceptible S. aureus (MSSA) and MRSA strains bearing quinolone-resistant target mutations, JNJ-Q2 displayed MICs ≤ 0.12 μg/ml, values 16- to 32-fold lower...

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Identifiers

PMID: 21911562
DOI: 10.1128/AAC.00470-11
PMCID: PMC3232800

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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