<i>Mycobacterium abscessus</i> and <i>M. avium</i> Trigger Toll-Like Receptor 2 and Distinct Cytokine Response in Human Cells

Abstract excerpt

Mycobacterium avium (MAV) and M. abscessus (MAB) are ubiquitous environmental organisms increasingly recognized to cause chronic lung disease in patients with apparently normal immune function. Little is yet known about their human pathophysiology. Our objective was to examine cytokine and chemokine responses (protein and gene expression) and signaling pathways triggered by reference and clinical isolates of MAB...