Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction of Coxiella burnetii Strains of Different Sources and Genotypes with Bovine and Human Monocyte-Derived Macrophages.

Frontiers in cellular and infection microbiology - 1 Jan 2017

Sobotta Katharina, Hillarius Kirstin, Jiménez Pablo H, Kerner Katharina, Heydel Carsten, Menge Christian

Abstract excerpt

Most human Q fever infections originate from small ruminants. By contrast, highly prevalent shedding of Coxiella (C.) burnetii by bovine milk rarely results in human disease. We hypothesized that primary bovine and human monocyte-derived macrophages (MDM) represent a suitable in vitro model for the identification of strain-specific virulence properties at the cellular level. Twelve different C. burnetii strains...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to Cattle

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cattle Diseases

Share to Coxiella burnetii

Share to Cytokines

Share to Host-Pathogen Interactions

Share to Macrophages

Share to Q Fever

Source

Open in PubMed Open full text

Identifiers

PMID: 29379776
DOI: 10.3389/fcimb.2017.00543
PMCID: PMC5771007

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction of Coxiella burnetii Strains of Different Sources and Genotypes with Bovine and Human Monocyte-Derived Macrophages.PMID 29379776Read ↗

Coxiella burnetii isolates originating from infected cattle induce a more pronounced proinflammatory cytokine response compared to isolates from infected goats and sheep.Semantic proximity Read ↗

Virulent<i>Coxiella burnetii</i>pathotypes productively infect primary human alveolar macrophagesSemantic proximity Read ↗

In vitro and in vivo infectious potential of coxiella burnetii: a study on Belgian livestock isolates.Semantic proximity Read ↗

Molecular epidemiology of Coxiella burnetii in French livestock reveals the existence of three main genotype clusters and suggests species-specific associations as well as regional stability.Semantic proximity Read ↗

From Q Fever to Coxiella burnetii Infection: a Paradigm ChangeSemantic proximity Read ↗

From neglected to dissected: How technological advances are leading the way to the study of Coxiella burnetii pathogenesis.Semantic proximity Read ↗

Mycobacterium Avium subsp. paratuberculosis isolates induce in vitro granuloma formation and show successful survival phenotype, common anti-inflammatory and antiapoptotic responses within ovine macrophages regardless of genotype or host of origin.Semantic proximity Read ↗

Permissiveness of bovine epithelial cells from lung, intestine, placenta and udder for infection with Coxiella burnetiiSemantic proximity Read ↗

Cytokine responses of bovine macrophages to diverse clinical Mycobacterium avium subspecies paratuberculosis strainsSemantic proximity Read ↗

Characterization of Coxiella burnetii strains from ruminants in a Galleria mellonella host-based modelSemantic proximity Read ↗

Comparative transcriptional analysis of human macrophages exposed to animal and human isolates of Mycobacterium avium subspecies paratuberculosis with diverse genotypes.Semantic proximity Read ↗

Anti-Inflammatory and Antiapoptotic Responses to Infection: A Common Denominator of Human and Bovine Macrophages Infected with<i>Mycobacterium avium</i>Subsp.<i>paratuberculosis</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.