Gene expression profiling of monocyte-derived macrophages following infection with<i>Mycobacterium avium</i>subspecies<i>avium</i>and<i>Mycobacterium avium</i>subspecies<i>paratuberculosis</i>

Abstract excerpt

Mycobacterium avium subspecies paratuberculosis (MAP) and Mycobacterium avium subspecies avium (MAA) represent two closely related intracellular bacteria with vastly different associated pathologies. MAA can cause severe respiratory infections in immune compromised humans but is nonpathogenic in ruminants and is more readily controlled by the bovine immune system than MAP. MAP causes a fatal wasting syndrome in...

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