Common and Unique Gene Expression Signatures of Human Macrophages in Response to Four Strains ofMycobacterium aviumThat Differ in Their Growth and Persistence Characteristics

Abstract excerpt

Classification of pathogenic species according to the distinct host transcriptional responses that they elicit may become a relevant tool for microarray-based diagnosis of infection. Individual strains of Mycobacterium avium, an opportunistic pathogen in humans, have previously been shown to differ in terms of growth and persistence. In order to cover a wide spectrum of virulence, we selected four M. avium...

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