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Article

Sp1 is required for glucose-induced transcriptional regulation of mouse vesicular glutamate transporter 2 gene.

Gastroenterology - 1 Jun 2008

Li Tao, Bai Liqun, Li Jing, Igarashi Suzu, Ghishan Fayez K

Abstract excerpt

BACKGROUND & AIMS: Vesicular glutamate transporter (VGLUT) has been reported to be involved in glucose-induced insulin secretion. It has been shown that glucose stimulates the expression of VGLUT isoform 2 (VGLUT2) in beta cells via transcriptional mechanism. In this study, we identified the mouse VGLUT2 (mVGLUT2) promoter and characterized the transcriptional mechanism of glucose-stimulated mVGLUT2 expression in...

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Identifiers

PMID: 18440316
DOI: 10.1053/j.gastro.2008.02.076
PMCID: PMC2747381

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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