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Article

G protein beta3 subunit C825T polymorphism modifies the presentation of temporal lobe epilepsy.

Acta neurologica Scandinavica. Supplementum - 1 Jan 2008

Osberg S, Melien O, Taubøll E, Gjerstad L

Abstract excerpt

PURPOSE: Experimental studies suggest a role of G protein-mediated signaling pathways in epileptogenesis. A genetic variation affecting the G protein subunit Gbeta3 denoted the C825T polymorphism has been reported to increase the signaling efficiency through G(i) proteins and to modify responses to certain drugs. The C825T polymorphism has also been associated with several diseases including hypertension,...

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Share to Anticonvulsants
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Heterotrimeric GTP-Binding Proteins

Share to Polymorphism, Genetic

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Source

Identifiers

PMID: 18439224
DOI: 10.1111/j.1600-0404.2008.01034.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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