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Article

Genetic study between SIRT1, PPARD, PGC-1alpha genes and Alzheimer's disease.

Journal of neurology - 1 May 2008

Helisalmi S, Vepsäläinen S, Hiltunen M, Koivisto A M, Salminen A, Laakso M, Soininen H

Abstract excerpt

Single nucleotide polymorphisms (SNPs) in three diabetes-related genes (SIRT1, PPARD, PGC-1alpha) were investigated with a case-control approach. To examine the genetic association of those genes with Alzheimer's disease (AD) risk, we used the TaqMan technique to genotype five SNP sites for SIRT1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18438697
DOI: 10.1007/s00415-008-0774-1

Genes

SIRT1
PGC
PPARD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18438697-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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