Article
Lack of genetic association between PPARG gene polymorphisms and Finnish late-onset Alzheimer's disease.
Neuroscience letters - 22 Aug 2008
Helisalmi Seppo, Tarvainen Timo, Vepsäläinen Saila, Koivisto Anne Mari, Hiltunen Mikko, Soininen Hilkka
Abstract excerpt
Single nucleotide polymorphisms (SNPs) in diabetes related peroxisome proliferator-activated receptor gamma (PPARG) gene were investigated with a case-control approach. To examine the genetic association of this gene with Alzheimer's disease (AD) risk, we used the TaqMan technique to genotype eight SNP sites for PPARG gene, in 538 Finnish AD cases and 672 controls and conducted a single allele and genotypic...
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