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Article

PPARD haplotype influences cholesterol metabolism but is no risk factor of Alzheimer's disease.

Neuroscience letters - 6 Nov 2006

Holzapfel Julia, Heun Reinhard, Lütjohann Dieter, Jessen Frank, Maier Wolfgang, Kölsch Heike

Abstract excerpt

Cholesterol metabolism is involved in Alzheimer's disease (AD) pathogenesis: increased cholesterol blood levels are detected in AD patients, and treatment with statins reduces the risk of AD. The peroxisome proliferator-activated receptor delta protein (PPARdelta), is a member of the steroid hormone super family of ligand-inducible transcription factors, and is of major relevance in lipid and cholesterol...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16979821
DOI: 10.1016/j.neulet.2006.08.029

Genes

PPARD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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