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Article

Variation in PCSK9, low LDL cholesterol, and risk of peripheral arterial disease.

Atherosclerosis - 1 Jan 2009

Folsom Aaron R, Peacock James M, Boerwinkle Eric

Abstract excerpt

BACKGROUND: We hypothesized that variants in PCSK9 that lower LDL cholesterol levels are associated with reduced prevalence and incidence of peripheral artery disease (PAD). METHODS: The Atherosclerosis Risk in Communities (ARIC) Study assessed risk factors and PCSK9 variants Y142X and C679X (rel...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18436227
DOI: 10.1016/j.atherosclerosis.2008.03.009
PMCID: PMC2607475

Genes

PCSK9

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18436227-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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