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Article

PCSK9 Variants in Familial Hypercholesterolemia: A Comprehensive Synopsis

23 Sept 2020

Abstract excerpt

Autosomal dominant familial hypercholesterolemia (FH) affects approximately 1/250 individuals and potentially leads to elevated blood cholesterol and a significantly increased risk of atherosclerosis. Along with improvements in detection and the increased early diagnosis and treatment, the serious burden of FH on families and society has become increasingly apparent. Since FH is strongly associated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33173529
DOI: 10.3389/fgene.2020.01020

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