Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Paraoxonase 1 gene promoter polymorphisms are associated with the extent of stenosis in coronary arteries.

Thrombosis research - 1 Jan 2009

Najafi Mohammad, Gohari Ladan Hosseani, Firoozrai Mohsen

Abstract excerpt

HDL-associated paraoxonase1 (PON1) is believed to be an important anti-oxidative enzyme in the retardation of atherosclerosis. In this study, we determined haplotypes of three SNPs within the PON1 gene promoter to elucidate association of functional sites with coronary artery disease (CAD). We applied a direct haplotyping procedure through ARMS (Amplification Refractory Mutation System) and RFLP (Restriction...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aryldialkylphosphatase
Share to Case-Control Studies
Share to Coronary Artery Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Coronary Stenosis

Share to Gene Frequency

Share to Haplotypes

Share to Promoter Regions, Genetic

Share to Risk Factors

Source

Identifiers

PMID: 18433845
DOI: 10.1016/j.thromres.2008.03.004

Genes

PON1
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Paraoxonase 1 gene promoter polymorphisms are associated with the extent of stenosis in coronary arteries.PMID 18433845Read ↗

Paraoxonase 1 (PON1) polymorphisms, haplotypes and activity in predicting cad risk in North-West Indian Punjabis.Semantic proximity Read ↗

Association between PON1 rs662 polymorphism and coronary artery disease.Semantic proximity Read ↗

Association between the severity of angiographic coronary artery disease and paraoxonase gene polymorphisms in the National Heart, Lung, and Blood Institute-sponsored Women's Ischemia Syndrome Evaluation (WISE) study.Semantic proximity Read ↗

Paraoxonase Arg 192 allele is an independent risk factor for three-vessel stenosis of coronary artery disease.Semantic proximity Read ↗

Variation at the paraoxonase gene locus contributes to carotid arterial wall thickness in subjects with familial hypercholesterolemia.Semantic proximity Read ↗

Paraoxonase gene cluster variations associated with coronary heart disease in Chinese Han women.Semantic proximity Read ↗

The relationship between paraoxonase1-192 polymorphism and activity with coronary artery disease.Semantic proximity Read ↗

Two- and three-locus haplotypes of the paraoxonase (PON1) gene are associated with coronary artery disease in Asian Indians.Semantic proximity Read ↗

The Q192R polymorphism of the paraoxonase 1 gene is a risk factor for coronary artery disease in Saudi subjects.Semantic proximity Read ↗

Paraoxonase activity, but not haplotype utilizing the linkage disequilibrium structure, predicts vascular disease.Semantic proximity Read ↗

A variant of human paraoxonase/arylesterase (HUMPONA) gene is a risk factor for coronary artery disease.Semantic proximity Read ↗

Mutations in the human paraoxonase 1 gene: frequencies, allelic linkages, and association with coronary artery disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.