Article
Paraoxonase Arg 192 allele is an independent risk factor for three-vessel stenosis of coronary artery disease.
Molecular biology reports - 1 Nov 2011
Vaisi-Raygani Asad, Ghaneialvar Hori, Rahimi Zohreh, Tavilani Haidar, Pourmotabbed Tayebeh, Shakiba Ebrahim, Vaisi-Raygani Aliakbar, Kiani Amir, Aminian Mahdi, Alibakhshi Reza, Bartels Cynthia
Abstract excerpt
The role of the paraoxonase (PON1) codon 192 polymorphism [glutamine (Q)/arginine (R)] in coronary artery disease (CAD) is controversial. The aim of the present study was to evaluate whether the PON1 gene polymorphism is an independent risk factor for severity of coronary artery disease in patients from west of Iran. The PON1-Arg-192 genotypes were detected by PCR-RFLP in 414 individuals undergoing their first...
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