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Article

Single tube optimisation of APOE genotyping based on melting curve analysis.

Clinical biochemistry - 1 Jul 2008

Francés Francesc, Portolés Olga, Sorlí José Vicente, Guillén Marisa, González José I, Corella Dolores

Abstract excerpt

OBJECTIVES: To develop and validate a single-tube protocol for APOE genotyping using fluorescent probes. DESIGN AND METHODS: We have designed and validated a hybrid, single-tube, SimpleProbe/FRET probe protocol that takes advantage of the different probe wavelength emissions. RESULTS: Our method offers high quality outcomes, minimum interferences between probe signals and is 100% concordant with the reference...

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Source

Identifiers

PMID: 18433724
DOI: 10.1016/j.clinbiochem.2008.03.010

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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