Article
Integrated single-label liquid-phase assay of APOE codons 112 and 158 and a lipoprotein study in British women.
Clinical chemistry - 1 Jul 2006
Abdollahi Mohammad Reza, Guthrie Philip A I, Smith George Davey, Lawlor Debbie A, Ebrahim Shah, Day Ian N M
Abstract excerpt
BACKGROUND: Apolipoprotein E (APOE) is an important element of lipid metabolism and, hence, cardiovascular disorders. APOE has 3 main allelic variants: epsilon3, epsilon4, and epsilon2. Of these, epsilon3 is the most common, followed by epsilon4 and epsilon2. The associations of these isoforms with cardiovascular disorders and Alzheimer disease have been widely studied in different populations. Most of the...
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