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Damaged DNA Binding Protein 2 Plays a Role in Breast Cancer Cell Growth

22 Apr 2008

Abstract excerpt

The Damaged DNA binding protein 2 (DDB2), is involved in nucleotide excision repair as well as in other biological processes in normal cells, including transcription and cell cycle regulation. Loss of DDB2 function may be related to tumor susceptibility. However, hypothesis of this study was that DDB2 could play a role in breast cancer cell growth, resulting in its well known interaction with the proliferative...

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PMID: 18431487
DOI: 10.1371/journal.pone.0002002

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