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Article

Emerging Roles of DDB2 in Cancer

18 Oct 2019

Abstract excerpt

Damage-specific DNA-binding protein 2 (DDB2) was originally identified as a DNA damage recognition factor that facilitates global genomic nucleotide excision repair (GG-NER) in human cells. DDB2 also contributes to other essential biological processes such as chromatin remodeling, gene transcription, cell cycle regulation, and protein decay. Recently, the potential of DDB2 in the development and progression of...

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PMID: 31635251
DOI: 10.3390/ijms20205168

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